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SELECTED PUBLICATIONS

Publications: Publicaciones

Fernández-Serra, Rocío, Lekouaghet, Amira, Peracho, Lorena, Yonesi, Mahdi; Alcazar, Alberto; Chioua, Mourad; Marco-Contelles, José; Pérez-Rigueiro, José, Rojo, Francisco, Panetsos, Fivos, Guinea, Gustavo, Gonzalez-Nieto, Daniel.  Permselectivity of Silk Fibroin Hydrogels for Advanced Drug Delivery neurotherapies. Biomacromolecules 2024, in press

Fernández-Serra R, Martínez-Alonso E, Alcázar A, Chioua M, Marco-Contelles J, Martínez-Murillo R, Ramos M, Guinea GV, González-Nieto D. Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations. Int J Mol Sci. 2022 Jul 4;23(13):7449. doi: 10.3390/ijms23137449.

Martínez-Alonso E, Escobar-Peso A, Aliena-Valero A, Torregrosa G, Chioua M, Fernández-Serra R, González-Nieto D, Ouahid Y, Salom JB, Masjuan J, Marco-Contelles J, Alcázar A. Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke. Antioxidants (Basel). 2022 Jun 16;11(6):1186. doi: 10.3390/antiox11061186.

Álvarez-López A, Colchero L, Elices M, Guinea G V, Pérez-Rigueiro J, González-Nieto D. Improved cell adhesion to activated vapor silanization-biofunctionalized ti-6al-4v surfaces with ECM-derived oligopeptides. Mater Sci Eng C, 2021 Dec, 112614. doi: 10.1016/j.msec.2021.112614.

Herrero M A, Gallego R, Ramos M, Lopez J M, de Arcas G, González-Nieto D. Sleep–wake cycle and EEG-based biomarkers during late neonate to adult transition. Brain Sci. 2021 Feb 11(3):298. doi: 10.3390/brainsci11030298.

Yonesi M, Garcia-Nieto M, Guinea G V, Panetsos F, Pérez-Rigueiro J, González-Nieto D. Silk Fibroin: An Ancient Material for Repairing the Injured Nervous System. Pharmaceutics. 2021 March 13(3):429. doi: 10.3390/pharmaceutics13030429.

Fernandez-Serra R, Gallego R, Lozano P, González-Nieto D. Hydrogels for neuroprotection and functional rewiring: a new era for brain engineering. Neural Regen Res. 2020 May;15(5):783-789. doi: 10.4103/1673-5374.268891.

González-Nieto D, Fernández-Serra R, Pérez-Rigueiro J, Panetsos F, Martinez-Murillo R, Guinea GV. Biomaterials to Neuroprotect the Stroke Brain: A Large Opportunity for Narrow Time Windows. Cells. 2020 Apr 26;9(5). pii: E1074. doi: 10.3390/cells9051074.

Martín-Martín Y, Fernández-García L, Sanchez-Rebato MH, Marí-Buyé N, Rojo FJ, Pérez-Rigueiro J, Ramos M, Guinea GV, Panetsos F, González-Nieto D. Evaluation of Neurosecretome from Mesenchymal Stem Cells Encapsulated in Silk Fibroin Hydrogels. Sci Rep. 2019 Jun 19;9(1):8801. doi: 10.1038/s41598-019-45238-4.

Fernández-García L, Pérez-Rigueiro J, Martinez-Murillo R, Panetsos F, Ramos M, Guinea GV, González-Nieto D. Cortical Reshaping and Functional Recovery Induced by Silk Fibroin Hydrogels-Encapsulated Stem Cells Implanted in Stroke Animals. Front Cell Neurosci. 2018 Sep 6;12:296. doi: 10.3389/fncel.2018.00296.

González-Nieto D, Fernández-García L, Pérez-Rigueiro J, Guinea GV, Panetsos F. Hydrogels-Assisted Cell Engraftment for Repairing the Stroke-Damaged Brain: Chimera or Reality. Polymers (Basel). 2018 Feb 13;10(2). pii: E184. doi: 10.3390/polym10020184.

Fernández-García L, Marí-Buyé N, Barios JA, Madurga R, Elices M, Pérez-Rigueiro J, Ramos M, Guinea GV, González-Nieto D. Safety and tolerability of silk fibroin hydrogels implanted into the mouse brain. Acta Biomater. 2016 Nov;45:262-275. doi: 10.1016/j.actbio.2016.09.003.

Barios JA, Pisarchyk L, Fernandez-Garcia L, Barrio LC, Ramos M, Martinez-Murillo R, Gonzalez-Nieto D. Long-term dynamics of somatosensory activity in a stroke model of distal middle cerebral artery oclussion. J Cereb Blood Flow Metab. 2016 Mar;36(3):606-20. doi: 10.1177/0271678X15606139.

González-Nieto D, Chang KH, Fasciani I, Nayak R, Fernandez-García L, Barrio LC, Cancelas JA. Connexins: Intercellular Signal Transmitters in Lymphohematopoietic Tissues. Int Rev Cell Mol Biol. 2015;318:27-62. doi: 10.1016/bs.ircmb.2015.06.001.

Chang KH, Sengupta A, Nayak RC, Duran A, Lee SJ, Pratt RG, Wellendorf AM, Hill SE, Watkins M, Gonzalez-Nieto D, Aronow BJ, Starczynowski DT, Civitelli R, Diaz-Meco MT, Moscat J, Cancelas JA. p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche. Cell Rep. 2014 Dec 24;9(6):2084-97. doi: 10.1016/j.celrep.2014.11.031.

Pizarro-Delgado J, Fasciani I, Temperan A, Romero M, González-Nieto D, Alonso-Magdalena P, Nualart-Marti A, Estil'les E, Paul DL, Martín-del-Río R, Montanya E, Solsona C, Nadal A, Barrio LC, Tamarit-Rodríguez J. Inhibition of connexin 36 hemichannels by glucose contributes to the stimulation of insulin secretion. Am J Physiol Endocrinol Metab. 2014 Jun 15;306(12):E1354-66. doi: 10.1152/ajpendo.00358.2013.

Nualart-Marti A, del Molino EM, Grandes X, Bahima L, Martin-Satué M, Puchal R, Fasciani I, González-Nieto D, Ziganshin B, Llobet A, Barrio LC, Solsona C. Role of connexin 32 hemichannels in the release of ATP from peripheral nerves. Glia. 2013 Dec;61(12):1976-89. doi: 10.1002/glia.22568.

Fasciani I, Temperán A, Pérez-Atencio LF, Escudero A, Martínez-Montero P, Molano J, Gómez-Hernández JM, Paino CL, González-Nieto D, Barrio LC. Regulation of connexin hemichannel activity by membrane potential and the extracellular calcium in health and disease. Neuropharmacology. 2013 Dec;75:479-90. doi: 10.1016/j.neuropharm.2013.03.040.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA. Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109

Gonzalez-Nieto D, Li L, Kohler A, Ghiaur G, Ishikawa E, Sengupta A, Madhu M, Arnett JL, Santho RA, Dunn SK, Fishman GI, Gutstein DE, Civitelli R, Barrio LC, Gunzer M, Cancelas JA. Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood. 2012 May 31;119(22):5144-54. doi: 10.1182/blood-2011-07-368506.

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